Fertility Topics Explained from the Experts at SFS
Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is “Why?”
Was it simply due to bad luck? How likely is the failure to recur in future attempts and what can be done differently to avoid it happening next time?.
It is an indisputable fact that any IVF procedure is at least as likely to fail as it is to succeed. Thus when it comes to outcome, luck is an undeniable factor. Notwithstanding, it is incumbent upon the treating physician to carefully consider and address the causes of IVF failure before proceeding to another attempt:
Certain causes of infertility are repetitive and thus cannot readily be reversed. Examples include advanced age of the woman; severe male infertility; immunologic infertility associated with alloimmune implantation dysfunction (especially if it is a complete DQ alpha genetic match between partners plus uterine natural killer cell activation (NKa).
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