Fertility Topics Explained from the Experts at SFS
In 2005, my associate Levent Keskintepe PhD and I introduced Preimplantation Genetic Testing (PGT) with the ability to identify all chromosomes in the embryo’s cells, into the field of IVF. This approach, which is now widely used throughout the world, permits selection of those embryos that are most likely to be competent, and has dramatically improved IVF success rates. However, some abnormal (or aneuploid) embryos are capable of autocorrecting and reverting to a normal karyotype (euploid) during intrauterine development and of then propagating healthy babies. This is because some embryos can harbor both aneuploid AND euploid cells. This combination of aneuploid plus euploid cells in the same embryo is referred to as “mosaicism.”
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